What Is Idarubicin?
Idarubicin is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
Idarubicin is used to treat acute myeloid leukemia (AML), a type of blood cancer.
Idarubicin may also be used for purposes not listed in this medication guide.
Idarubicin may cause dangerous effects on your heart. Call your doctor at once if you have chest pain, shortness of breath (even with mild exertion), swelling, or rapid weight gain.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when idarubicin is injected.Call your doctor if you have irritation or skin changes where the injection was given.
Idarubicin can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).
Before you are treated with idarubicin, tell your doctor about all other cancer medications and treatments you have received, including radiation.
You should not receive idarubicin if you are allergic to it.
To make sure idarubicin is safe for you, tell your doctor if you have:
- heart disease (idarubicin may cause dangerous effects on your heart);
- kidney disease;
- liver disease;
- weak immune system (caused by disease or by using certain medicines); or
- if you have been treated before with doxorubicin, daunorubicin, epirubicin, idarubicin, or mitoxantrone.
Do not use idarubicin if you are pregnant.It could harm the unborn baby. Use effective birth control to avoid pregnancy during your treatment with idarubicin. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.
It is not known whether idarubicin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Idarubicin Side Effects
Get emergency medical help if you havesigns of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- irritation or skin changes where the injection was given;
- shortness of breath (even with mild exertion), swelling, rapid weight gain;
- fever, swollen gums, painful mouth sores, pain when swallowing;
- skin sores, cold or flu symptoms, cough, trouble breathing;
- rectal pain, blood in your stools, diarrhea;
- severe nausea, vomiting, or stomach cramps;
- easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
- change in your mental state, seizure (convulsions);
- joint pain and stiffness; or
- jaundice (yellowing of the skin or eyes).
Common side effects may include:
- mild stomach discomfort;
- numbness or tingling;
- headache; or
- temporary hair loss.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
This medicine can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
Do not receive a "live" vaccine while using idarubicin,or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
Other drugs may interact with idarubicin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Idarubicin is injected into a vein through an IV. A healthcare provider will give you this injection.
Idarubicin is usually given together with other cancer medications. You may be given other medications to prevent nausea, vomiting, or infections.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when idarubicin is injected.
If any of this medication accidentally gets on your skin, wash it thoroughly with soap and warm water.
Idarubicin can lower blood cells that help your body fight infections and help your blood to clot. This can make it easier for you to bleed from an injury or get sick from being around others who are ill.Your blood will need to be tested often.Your kidney and liver function may also need to be tested.
Your heart function may also need to be checked using an electrocardiograph or ECG (sometimes called an EKG).
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Call your doctor for instructions if you miss an appointment for your idarubicin injection.
Copyright 1996-2019 Cerner Multum, Inc.
Video: Increased Idarubicin Dosage During Consolidation Therapy
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