How do pills work?
For people far from medicine, it is a mystery how a small pill affects the body. And if, for example, citramon enters the stomach, how does he manage to cope with a headache? The objectives of the pill are to cover the diseased organ with their action, carefully heal it without harming the body.
Present the debugged mechanism of work on the example of analgin. A person is afflicted with pain in an inflamed joint, later on this very place there is a reddening, noticeable swelling. But after taking analgin pain begins to pass and then fades away. How it works?
Principle of transportation
The tablet initially appears in the stomach. Water and enzymes will provoke its disintegration, the irreversible process of "releasing" metamizole sodium will start. This tricky substance, it is actively working in our chosen anesthetic for the analysis. Penetrating from the stomach into the blood, it is absorbed and spread throughout the body. It is your blood that will eventually deliver the drug to the affected area, i.e. into the joint.
How do pills work? The basis of the discomfort-delivering inflammation is a chemical reaction. Its members are prostaglandins. These are substances that irritate nerves. A stream of impulses tends to the nervous system, a person accepts them, interpreting them as pain. The active in the tablet, metamizole sodium, has a blocking effect on these biological substances. The mechanism of action of tablets breaks the chain of the inflammatory process, providing an anti-inflammatory and tangible anti-pain effect.
The tablet was created in order to reach the goal, dissolve, freeing its active components, and send them on a further "journey" so that the bloodstream brings them to the suffering organ, healing it.
Principle of substitution
Consider the mechanism of the functioning of beta-blockers, which operate on the principle of substitution or "competitive antagonism." The essence of this principle lies in the fact that substances trapped in the body, displace other substances that are similar to them. In the case of a beta blocker, this is adrenaline, which the drug must supplant.Adrenaline is captured by special receptors, and the beta blocker is identical in structure to adrenaline. At the same time, the beta-blocker itself has no effect on the body. It is used to reduce the level of adrenaline in the blood. Thus, drugs with the principle of substitution are created to deceive the receptors of our body, reducing the excess amount of substances in it.
It should be noted that in order to replace one substance with another, a large dose may be needed. After all, receptors will capture molecules until their production stops. Therefore, this principle is called competitive.
Some drugs have combined mechanisms of action. These include herbal preparations. Plants are a set of chemical compounds, and in spite of the seeming benefits of natural components, we should not forget that the combined mechanisms of drug action often lead to side effects than isolated ones. All this is due to the unpredictability of the effects of such drugs on the body. Therefore, doctors often recommend consulting before taking herbal preparations.